Recently, copper and manganese-containing systems are recognized as active and selective catalysts in many oxidation reactions. The main idea of this study is to obtain more information about γ-Al2O3 supported Cu-La catalysts and to evaluate their activity to simultaneous oxidation of CO, CH3OH and dimethyl ether (DME). The catalysts were synthesized by impregnation of support with a mixed aqueous solution of nitrates of copper, manganese and lanthanum under different conditions. XRD, HRTEM/EDS, TPR and thermal analysis were performed to investigate catalysts’ bulk and surface properties. The texture characteristics were determined by Quantachrome Instruments NOVA 1200e specific surface area and pore analyzer. The catalytic measurements of single compounds oxidation were carried out on continuous flow equipment with a four-channel isothermal stainless steel reactor in a wide temperature range. On the basis of XRD analysis and HRTEM/EDS, it was concluded that the active component of the mixed Cu-Mn-La/γ–alumina catalysts strongly depends on the Cu/Mn molar ratio and consisted of at least four compounds – CuO, La2O3, MnO2 and Cu1.5Mn1.5O4. A homogeneous distribution of the active component on the carrier surface was found. The chemical composition strongly influenced catalytic properties. This influence was quite variable with regards to the different processes.
 Y. Nishihata, J. Mizuki, T. Akao, H. Tanaka, M. Uenishi, M. Kimura, N. Hamada, “Self-regeneration of a Pd-perovskite catalyst for automotive emissions control”, Nature, 418 (6894), pp. 164-167 2002.
 H. Tanaka, M. Misono, “Advances in designing perovskite catalysts”, Current Opinion in Solid State and Materials Science, 5 (5), pp. 381-387, 2001.
 M. Stoyanova ,P. Konova, P. Nikolov, A. Naydenov, St. Christoskova, D. Mehandjiev “Alumina-supported nickel oxide for ozone decomposition and catalytic ozonation of CO and VOCs” , Chemical Engineering Journal 122 (1-2) , pp 41-46, 2006.
 S. Moreau, J. Choisnet, F. Beguin, J., “Development of LaxMOy nanoparticles dispersed in a layered silicate matrix”, Phys. Chem. Solids, 57, pp. 1049-1056, 1996.
 E. A. Lombardo, M.A. Ulla, “Perovskite oxides in catalysis: Past, present and future”, Res. Chem. lntermed., 24 (5), pp. 581-592, 1998.
 X. Chen, S.A.C. Carabineiro, P.B. Tavares, J.J.M. Orfao, M.F.R. Pereira, J.L. Figueired, “Catalytic oxidation of ethyl acetate over La-Co and La-Cu oxides”, J. Envir. Chem. Eng., 2, pp. 344-355, 2014.
 R. Prasad, P. Singh, “A Review on CO oxidation over copper chromite catalyst”, Catal. Rev.: Sci. Eng., 54, pp. 224–279, 2012.
 A. Urbutis, S. Kitrys, “Structure and activity of CuO catalysts promoted with CeO2 and La2O3 for complete oxidation of VOCs”, Chemija., 24 (2), pp. 111–117, 2013.
 S. Mentus, D. Jeli, V. Grudi, “Lanthanum nitrate decomposition by both temperature programmed heating and citrate gel combustion. Comparative study”, J. Therm. Anal. Calorim., 90 (2), pp.393–39, 2007.
 H.E. Runxia, H. Jiang, W.U. Fang, K. Zhi, N. Wang, C. Zhou, Q. Liu, “Effect of doping rare earth oxide on performance of copper-manganese catalysts for water-gas shift reaction“, J. Rare Earths, 32 (4), pp. 298-305, 2014.