Scholarly Research Excellence

Digital Open Science Index

Commenced in January 2007 Frequency: Monthly Edition: International Publications Count: 29023


Select areas to restrict search in scientific publication database:
1474
Preparation and Characterization of M. × Piperita L. Oil Based Gel Formulation
Abstract:
The essential oil of M. × piperita L. was formulated into a topical gel. The prepared gel was characterized for its pH, viscosity, spreadiblity, consistency and extrudiblity, while its stability was evaluated under different temperature conditions. The prepared M. × piperita oil gel was clear and transparent. The pH value of developed gel was 6.6, while its viscosity was 1200 cP. Spreadability and consistency of the M. × piperita oil gel was 10.7 g.cm/sec and 7 mm, respectively. The prepared gel showed good extrudiblity. During the stability studies, no significant change in pH and viscosity as a function of time for gel was observed, indicating stability of prepared formulation. The gel developed in this study is expected to forward the usage of M. × piperita essential towards commercial application.
Digital Object Identifier (DOI):

References:

[1] Baris O, G├╝ll├╝ce M, Shahin F, ├ûzer H, Kilic H, ├ûzkan H, Sökmen M, ├ûzber T (2006). Biological activities of the essential oil and methanol extract of Achillea biebersteinii (Asteraceae) Turk J Biol 30: 65-73.
[2] Kumar P, Mishra S, Malik A, Satya S (2011). Repellent, larvicidal and pupicidal properties of essential oils and their formulations against the housefly, Musca domestica. Med Vet Entomol
[3] Werka JS, Boehme AK, Setzer WN (2007). Biological activities of essential oils from Monteverde, Costa Rica. Nat Prod Commun 2: 1215- 1219.
[4] Ormancey X, Sisalli S, Coutiere P (2001). Formulation of essential oils in functional perfumery. Parfums Cosmetiques Actualites 157: 30-40.
[5] Bagwe RP, Kanicky JR, Palla BJ, Pantajali PK, Shah DO (2001). Improved drug delivery using microemulsions: rationale, recent progress and new horizons. Crit Rev Ther Drug 18: 77-140.
[6] Manou I, Bouillard L, Devleschouwer MJ, Barel AG (1998). Evaluation of the preservative properties of Thymus vulgaris essential oil in topically applied formulations under a challenge test. J Appl Microbiol 84: 368 376.
[7] Orafidiya LO, Oyedele AO, Shittu AO, Elujoba AA(2001). The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil. Int J Pharm 224: 177-83.
[8] Oyedele, AO, Gbolade AA, Sosan MB, Adewoyin FB, Soyelu OL, Orafidiya OO (2002). Formulation of an effective mosquitorepellent topical product from lemongrass oil. Phytomedicine 9: 259-262.
[9] Quinones D, Ghaly ES (2008). Formulation and characterization of nystatin gel. P R Health Sci J 27: 61-67.
[10] Kumar S, Himmelsten K (1995) Modification of in situ gelling behavior of carbopol solution by Hydroxypropyl methyl cellulose. J Pharm Sci 84:344-8.
[11] Rama rao P, Diwan PV (1998) Formulation and In vivo Evaluation of Polymeric Film Diktiazim Hydrochloride and Indomethacin for Transdermal Administration. Drug Dev. Ind Pharm 24:327-338.
[12] Lee B, Choi W, Lee S, Park B (2001). Fumigant toxicity of essential oils and their constituent compounds towards the rice weevil, S. oryzae (L.). Crop Prot 20: 317-320.
[13] Bakkali F, Averbeck S, Averbeck D, Idaomar M (2008). Biological effects of essential oils. Rev Food Chem Toxicol 46: 446-475.
[14] Kumar P, Mishra S, Malik A, Satya S (2012). Efficacy of Mentha ×piperita and Mentha citrata essential oils against housefly, Musca domestica L. Ind Crop Prod 39 (2012) 106- 112
[15] Shivhare UD, Jain KB, mathur V B, Bhusari K P, Roy A (2009). Formulation development and evaluation of diclofenac sodium gel using water soluble polyacrylamide polymer. Dig J Nanomater Bios 4: 285- 290.
[16] William L (2000) Remington: The Science and Practice of Pharmacy. 20th edition. Mack Publishing Company. Easton, PA.
[17] Bhanu PV, Shanmugam V, Lakshmi P K (2011) Development And Optimization Of Novel Diclofenac Emulgel for Topical Drug Delivery . Internat J Compre Pharmacy 9 (10): 1-4.
[18] ICH Harmonized Tripartite Guidelines (2003) Stability Testing of New Drug Substances and Products. ICH Committee 8.
[19] Kumar R, Patil MB, Patil SR, Paschapur MS (2009) Evaluation of Anacardium occidentale gum as gelling agent in Aceclofenac Gel. Int J ChemTech Res Coden (USA): Ijprif. 1 (3): 695-704.
Vol:12 No:11 2018Vol:12 No:10 2018Vol:12 No:09 2018Vol:12 No:08 2018Vol:12 No:07 2018Vol:12 No:06 2018Vol:12 No:05 2018Vol:12 No:04 2018Vol:12 No:03 2018Vol:12 No:02 2018Vol:12 No:01 2018
Vol:11 No:12 2017Vol:11 No:11 2017Vol:11 No:10 2017Vol:11 No:09 2017Vol:11 No:08 2017Vol:11 No:07 2017Vol:11 No:06 2017Vol:11 No:05 2017Vol:11 No:04 2017Vol:11 No:03 2017Vol:11 No:02 2017Vol:11 No:01 2017
Vol:10 No:12 2016Vol:10 No:11 2016Vol:10 No:10 2016Vol:10 No:09 2016Vol:10 No:08 2016Vol:10 No:07 2016Vol:10 No:06 2016Vol:10 No:05 2016Vol:10 No:04 2016Vol:10 No:03 2016Vol:10 No:02 2016Vol:10 No:01 2016
Vol:9 No:12 2015Vol:9 No:11 2015Vol:9 No:10 2015Vol:9 No:09 2015Vol:9 No:08 2015Vol:9 No:07 2015Vol:9 No:06 2015Vol:9 No:05 2015Vol:9 No:04 2015Vol:9 No:03 2015Vol:9 No:02 2015Vol:9 No:01 2015
Vol:8 No:12 2014Vol:8 No:11 2014Vol:8 No:10 2014Vol:8 No:09 2014Vol:8 No:08 2014Vol:8 No:07 2014Vol:8 No:06 2014Vol:8 No:05 2014Vol:8 No:04 2014Vol:8 No:03 2014Vol:8 No:02 2014Vol:8 No:01 2014
Vol:7 No:12 2013Vol:7 No:11 2013Vol:7 No:10 2013Vol:7 No:09 2013Vol:7 No:08 2013Vol:7 No:07 2013Vol:7 No:06 2013Vol:7 No:05 2013Vol:7 No:04 2013Vol:7 No:03 2013Vol:7 No:02 2013Vol:7 No:01 2013
Vol:6 No:12 2012Vol:6 No:11 2012Vol:6 No:10 2012Vol:6 No:09 2012Vol:6 No:08 2012Vol:6 No:07 2012Vol:6 No:06 2012Vol:6 No:05 2012Vol:6 No:04 2012Vol:6 No:03 2012Vol:6 No:02 2012Vol:6 No:01 2012
Vol:5 No:12 2011Vol:5 No:11 2011Vol:5 No:10 2011Vol:5 No:09 2011Vol:5 No:08 2011Vol:5 No:07 2011Vol:5 No:06 2011Vol:5 No:05 2011Vol:5 No:04 2011Vol:5 No:03 2011Vol:5 No:02 2011Vol:5 No:01 2011
Vol:4 No:12 2010Vol:4 No:11 2010Vol:4 No:10 2010Vol:4 No:09 2010Vol:4 No:08 2010Vol:4 No:07 2010Vol:4 No:06 2010Vol:4 No:05 2010Vol:4 No:04 2010Vol:4 No:03 2010Vol:4 No:02 2010Vol:4 No:01 2010
Vol:3 No:12 2009Vol:3 No:11 2009Vol:3 No:10 2009Vol:3 No:09 2009Vol:3 No:08 2009Vol:3 No:07 2009Vol:3 No:06 2009Vol:3 No:05 2009Vol:3 No:04 2009Vol:3 No:03 2009Vol:3 No:02 2009Vol:3 No:01 2009
Vol:2 No:12 2008Vol:2 No:11 2008Vol:2 No:10 2008Vol:2 No:09 2008Vol:2 No:08 2008Vol:2 No:07 2008Vol:2 No:06 2008Vol:2 No:05 2008Vol:2 No:04 2008Vol:2 No:03 2008Vol:2 No:02 2008Vol:2 No:01 2008
Vol:1 No:12 2007Vol:1 No:11 2007Vol:1 No:10 2007Vol:1 No:09 2007Vol:1 No:08 2007Vol:1 No:07 2007Vol:1 No:06 2007Vol:1 No:05 2007Vol:1 No:04 2007Vol:1 No:03 2007Vol:1 No:02 2007Vol:1 No:01 2007