Open Science Research Excellence
%0 Journal Article
%A Young-Seok Choi
%D 2015 
%J  International Journal of Medical, Health, Biomedical, Bioengineering and Pharmaceutical Engineering
%B World Academy of Science, Engineering and Technology
%I International Science Index 101, 2015
%T Assessing Complexity of Neuronal Multiunit Activity by Information Theoretic Measure
%V 101
%X This paper provides a quantitative measure of the
time-varying multiunit neuronal spiking activity using an entropy
based approach. To verify the status embedded in the neuronal activity
of a population of neurons, the discrete wavelet transform (DWT) is
used to isolate the inherent spiking activity of MUA. Due to the
de-correlating property of DWT, the spiking activity would be
preserved while reducing the non-spiking component. By evaluating
the entropy of the wavelet coefficients of the de-noised MUA, a
multiresolution Shannon entropy (MRSE) of the MUA signal is
developed. The proposed entropy was tested in the analysis of both
simulated noisy MUA and actual MUA recorded from cortex in rodent
model. Simulation and experimental results demonstrate that the
dynamics of a population can be quantified by using the proposed

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