Open Science Research Excellence
%0 Journal Article
%A Ibrahim Aly  and  Rabab Zalat and  Bahaa EL Deen W. El Aswad and   Ismail M. Moharm  and  Basam M. Masoud and  Tarek Diab
%D 2013 
%J  International Journal of Medical and Health Sciences
%B World Academy of Science, Engineering and Technology
%I International Science Index 84, 2013
%T Novel Nanomagnetic Beads Based - Latex Agglutination Assay for Rapid Diagnosis of Human Schistosomiasis Haematobium
%U http://waset.org/publications/9997052
%V 84
%X The objective of the present study was to evaluate the novel nanomagnetic beads based–latex agglutination assay (NMB-LAT) as a simple test for diagnosis of S. haematobium as well as standardize the novel nanomagnetic beads based –ELISA (NMB-ELISA). According to urine examination this study included 85 S. haematobium infected patients, 30 other parasites infected patients and 25 negative control samples. The sensitivity of novel NMB-LAT was 82.4% versus 96.5% and 88.2% for NMB-ELISA and currently used sandwich ELISA respectively. The specificity of NMB-LAT was 83.6% versus 96.3% and 87.3% for NMB-ELISA and currently used sandwich ELISA respectively. In conclusion, the novel NMB-ELISA is a valuable applicable diagnostic technique for diagnosis of human schistosomiasis haematobium. The novel NMB-ELISA assay is a suitable applicable diagnostic method in field survey especially when followed by ELISA as a confirmatory test in query false negative results. Trials are required to increase the sensitivity and specificity of NMB-ELISA assay.

%P 977 - 983