Open Science Research Excellence

Open Science Index

Commenced in January 2007 Frequency: Monthly Edition: International Publications Count: 29296

Select areas to restrict search in scientific publication database:
Odor Discrimination Using Neural Decoding of Olfactory Bulbs in Rats
This paper presents a novel method for inferring the odor based on neural activities observed from rats- main olfactory bulbs. Multi-channel extra-cellular single unit recordings were done by micro-wire electrodes (tungsten, 50μm, 32 channels) implanted in the mitral/tufted cell layers of the main olfactory bulb of anesthetized rats to obtain neural responses to various odors. Neural response as a key feature was measured by substraction of neural firing rate before stimulus from after. For odor inference, we have developed a decoding method based on the maximum likelihood (ML) estimation. The results have shown that the average decoding accuracy is about 100.0%, 96.0%, 84.0%, and 100.0% with four rats, respectively. This work has profound implications for a novel brain-machine interface system for odor inference.
Digital Object Identifier (DOI):


[1] P. Dayan, L.F. Abbott, and L. Abbott, Theoretical neuroscience: Computational and mathematical modeling of neural systems, MIT press Cambridge, MA:, 2001.
[2] A. Pouget, S.A. Fisher, and T.J. Sejnowski, "Egocentric spatial representation in early vision," Journal of Cognitive Neuroscience, vol. 5, pp. 150-150, 1993.
[3] M.D. Serruya, N.G. Hatsopoulos, L. Paninski, M.R. Fellows, and J.P. Donoghue, "Brain-machine interface: Instant neural control of a movement signal," Nature, vol. 416, no. 6877, pp. 141-142, 2002.
[4] W. Wu, M.J. Black, Y. Gao, E. Bienenstock, M. Serruya, A. Shaikhouni, and J.P. Donoghue, "Neural decoding of cursor motion using a Kalman filter," in Advances in Neural Information Processing Systems 15: Proceedings of the 2002 Conference. The MIT Press, 2003, p. 133.
[5] A. Pouget, K. Zhang, S. Deneve, and P.E. Latham, "Statistically efficient estimation using population coding," Neural Computation, vol. 10, no. 2, pp. 373-401, 1998.
[6] J. Wessberg, C.R. Stambaugh, J.D. Kralik, P.D. Beck, M. Laubach, J.K. Chapin, J. Kim, S.J. Biggs, M.A. Srinivasan, and M.A.L. Nicolelis, "Real-time prediction of hand trajectory by ensembles of cortical neurons in primates," Nature, vol. 408, no. 6810, pp. 361-365, 2000.
[7] L. Paninski, M.R. Fellows, N.G. Hatsopoulos, and J.P. Donoghue, "Spatiotemporal tuning of motor cortical neurons for hand position and velocity," Journal of Neurophysiology, vol. 91, no. 1, pp. 515, 2004.
[8] A.P. Georgopoulos, A.B. Schwartz, and R.E. Kettner, "Neuronal population coding of movement direction," Science, vol. 233, no. 4771, pp. 1416, 1986.
[9] M. Jazayeri and J.A. Movshon, "Optimal representation of sensory information by neural populations," Nature Neuroscience, vol. 9, no. 5, pp. 690-696, 2006.
[10] H.C. Shin, V. Aggarwal, S. Acharya, M.H. Schieber, and N.V. Thakor, "Neural Decoding of Finger Movements Using Skellam- Based Maximum-Likelihood Decoding," Biomedical Engineering, IEEE Transactions on, vol. 57, no. 3, pp. 754-760, 2010.
[11] M. Leon and B.A. Johnson, "Olfactory coding in the mammalian olfactory bulb," Brain Research Reviews, vol. 42, no. 1, pp. 23-32, 2003.
[12] L.B. Buck, "Information coding in the vertebrate olfactory system," Annual review of neuroscience, vol. 19, no. 1, pp. 517-544, 1996.
[13] D.Y. Lin, S.D. Shea, and L.C. Katz, "Representation of natural stimuli in the rodent main olfactory bulb," Neuron, vol. 50, no. 6, pp. 937-949, 2006.
[14] R. Tabor, E. Yaksi, J.M. Weislogel, and R.W. Friedrich, "Processing of odor mixtures in the zebrafish olfactory bulb," Journal of Neuroscience, vol. 24, no. 29, pp. 6611, 2004.
[15] M. Meredith, "Patterned response to odor in mammalian olfactory bulb: the influence of intensity," Journal of neurophysiology, vol. 56, no. 3, pp. 572, 1986.
Vol:13 No:02 2019Vol:13 No:01 2019
Vol:12 No:12 2018Vol:12 No:11 2018Vol:12 No:10 2018Vol:12 No:09 2018Vol:12 No:08 2018Vol:12 No:07 2018Vol:12 No:06 2018Vol:12 No:05 2018Vol:12 No:04 2018Vol:12 No:03 2018Vol:12 No:02 2018Vol:12 No:01 2018
Vol:11 No:12 2017Vol:11 No:11 2017Vol:11 No:10 2017Vol:11 No:09 2017Vol:11 No:08 2017Vol:11 No:07 2017Vol:11 No:06 2017Vol:11 No:05 2017Vol:11 No:04 2017Vol:11 No:03 2017Vol:11 No:02 2017Vol:11 No:01 2017
Vol:10 No:12 2016Vol:10 No:11 2016Vol:10 No:10 2016Vol:10 No:09 2016Vol:10 No:08 2016Vol:10 No:07 2016Vol:10 No:06 2016Vol:10 No:05 2016Vol:10 No:04 2016Vol:10 No:03 2016Vol:10 No:02 2016Vol:10 No:01 2016
Vol:9 No:12 2015Vol:9 No:11 2015Vol:9 No:10 2015Vol:9 No:09 2015Vol:9 No:08 2015Vol:9 No:07 2015Vol:9 No:06 2015Vol:9 No:05 2015Vol:9 No:04 2015Vol:9 No:03 2015Vol:9 No:02 2015Vol:9 No:01 2015
Vol:8 No:12 2014Vol:8 No:11 2014Vol:8 No:10 2014Vol:8 No:09 2014Vol:8 No:08 2014Vol:8 No:07 2014Vol:8 No:06 2014Vol:8 No:05 2014Vol:8 No:04 2014Vol:8 No:03 2014Vol:8 No:02 2014Vol:8 No:01 2014
Vol:7 No:12 2013Vol:7 No:11 2013Vol:7 No:10 2013Vol:7 No:09 2013Vol:7 No:08 2013Vol:7 No:07 2013Vol:7 No:06 2013Vol:7 No:05 2013Vol:7 No:04 2013Vol:7 No:03 2013Vol:7 No:02 2013Vol:7 No:01 2013
Vol:6 No:12 2012Vol:6 No:11 2012Vol:6 No:10 2012Vol:6 No:09 2012Vol:6 No:08 2012Vol:6 No:07 2012Vol:6 No:06 2012Vol:6 No:05 2012Vol:6 No:04 2012Vol:6 No:03 2012Vol:6 No:02 2012Vol:6 No:01 2012
Vol:5 No:12 2011Vol:5 No:11 2011Vol:5 No:10 2011Vol:5 No:09 2011Vol:5 No:08 2011Vol:5 No:07 2011Vol:5 No:06 2011Vol:5 No:05 2011Vol:5 No:04 2011Vol:5 No:03 2011Vol:5 No:02 2011Vol:5 No:01 2011
Vol:4 No:12 2010Vol:4 No:11 2010Vol:4 No:10 2010Vol:4 No:09 2010Vol:4 No:08 2010Vol:4 No:07 2010Vol:4 No:06 2010Vol:4 No:05 2010Vol:4 No:04 2010Vol:4 No:03 2010Vol:4 No:02 2010Vol:4 No:01 2010
Vol:3 No:12 2009Vol:3 No:11 2009Vol:3 No:10 2009Vol:3 No:09 2009Vol:3 No:08 2009Vol:3 No:07 2009Vol:3 No:06 2009Vol:3 No:05 2009Vol:3 No:04 2009Vol:3 No:03 2009Vol:3 No:02 2009Vol:3 No:01 2009
Vol:2 No:12 2008Vol:2 No:11 2008Vol:2 No:10 2008Vol:2 No:09 2008Vol:2 No:08 2008Vol:2 No:07 2008Vol:2 No:06 2008Vol:2 No:05 2008Vol:2 No:04 2008Vol:2 No:03 2008Vol:2 No:02 2008Vol:2 No:01 2008
Vol:1 No:12 2007Vol:1 No:11 2007Vol:1 No:10 2007Vol:1 No:09 2007Vol:1 No:08 2007Vol:1 No:07 2007Vol:1 No:06 2007Vol:1 No:05 2007Vol:1 No:04 2007Vol:1 No:03 2007Vol:1 No:02 2007Vol:1 No:01 2007