Highly Sensitive Label Free Biosensor for Tumor Necrosis Factor
We present a label-free biosensor based on
electrochemical impedance spectroscopy for the detection of proinflammatory
cytokine Tumor Necrosis Factor (TNF-α). Secretion of
TNF-α has been correlated to the onset of various diseases including
rheumatoid arthritis, Crohn-s disease etc. Gold electrodes were
patterned on a silicon substrate and self assembled monolayer of
dithiobis-succinimidyl propionate was used to develop the biosensor
which achieved a detection limit of ~57fM. A linear relationship was
also observed between increasing TNF-α concentrations and chargetransfer
resistance within a dynamic range of 1pg/ml – 1ng/ml.
Tumor necrosis factor, electrochemical impedance
spectroscopy, label free, self assembled monolayer
Creep Transition in a Thin Rotating Disc Having Variable Density with Inclusion
Creep stresses and strain rates have been obtained
for a thin rotating disc having variable density with inclusion by
using Seth-s transition theory. The density of the disc is assumed to
vary radially, i.e. ( ) 0 ¤ü ¤ü r/b m - = ; ¤ü 0 and m being real positive
constants. It has been observed that a disc, whose density increases
radially, rotates at higher angular speed, thus decreasing the
possibility of a fracture at the bore, whereas for a disc whose
density decreases radially, the possibility of a fracture at the bore
Elastic-Plastic, Inclusion, Rotating disc, Stress,Strain rates, Transition, variable density.
Design, Analysis and Modeling of Dual Band Microstrip Loop Antenna Using Defective Ground Plane
Present wireless communication demands compact and intelligent devices with multitasking capabilities at affordable cost. The focus in the presented paper is on a dual band antenna for wireless communication with the capability of operating at two frequency bands with same structure. Two resonance frequencies are observed with the second operation band at 4.2GHz approximately three times the first resonance frequency at 1.5GHz. Structure is simple loop of microstrip line with characteristic impedance 50 ohms. The proposed antenna is designed using defective ground structure (DGS) and shows the nearly one third reductions in size as compared to without DGS. This antenna was simulated on electromagnetic (EM) simulation software and fabricated using microwave integrated circuit technique on RT-Duroid dielectric substrate (εr= 2.22) of thickness (H=15 mils). The designed antenna was tested on automatic network analyzer and shows the good agreement with simulated results. The proposed structure is modeled into an equivalent electrical circuit and simulated on circuit simulator. Subsequently, theoretical analysis was carried out and simulated. The simulated, measured, equivalent circuit response, and theoretical results shows good resemblance. The bands of operation draw many potential applications in today’s wireless communication.
Defective Ground plane, Dual band, Loop Antenna, Microstrip antenna, Resonance frequency.
Elastic-Plastic Transition in a Thin Rotating Disc with Inclusion
Stresses for the elastic-plastic transition and fully
plastic state have been derived for a thin rotating disc with inclusion
and results have been discussed numerically and depicted graphically.
It has been observed that the rotating disc with inclusion and made of
compressible material requires lesser angular speed to yield at the
internal surface whereas it requires higher percentage increase in
angular speed to become fully plastic as compare to disc made of
Angular speed, Elastic-Plastic, Inclusion, Rotatingdisc, Stress, Transition.
Application of Artificial Intelligence Techniques for Dissolved Gas Analysis of Transformers-A Review
The gases generated in oil filled transformers can be
used for qualitative determination of incipient faults. The Dissolved
Gas Analysis has been widely used by utilities throughout the world
as the primarily diagnostic tool for transformer maintenance. In this
paper, various Artificial Intelligence Techniques that have been used
by the researchers in the past have been reviewed, some conclusions
have been drawn and a sequential hybrid system has been proposed.
The synergy of ANN and FIS can be a good solution for reliable
results for predicting faults because one should not rely on a single
technology when dealing with real–life applications.
Dissolved Gas Analysis, Artificial IntelligenceTechniques, Incipient Faults, Transformer Fault Diagnosis, andHybrid Systems.