Open Science Research Excellence

S H Sabzpoushan

Publications

3

Publications

3
7749
Simulating Action Potential as a Linear Combination of Gating Dynamics
Abstract:

In this research we show that the dynamics of an action potential in a cell can be modeled with a linear combination of the dynamics of the gating state variables. It is shown that the modeling error is negligible. Our findings can be used for simplifying cell models and reduction of computational burden i.e. it is useful for simulating action potential propagation in large scale computations like tissue modeling. We have verified our finding with the use of several cell models.

Keywords:
Linear model, Action potential, gating dynamics.
2
11542
Involving Action Potential Morphology on a New Cellular Automata Model of Cardiac Action Potential Propagation
Abstract:
Computer modeling has played a unique role in understanding electrocardiography. Modeling and simulating cardiac action potential propagation is suitable for studying normal and pathological cardiac activation. This paper presents a 2-D Cellular Automata model for simulating action potential propagation in cardiac tissue. We demonstrate a novel algorithm in order to use minimum neighbors. This algorithm uses the summation of the excitability attributes of excited neighboring cells. We try to eliminate flat edges in the result patterns by inserting probability to the model. We also preserve the real shape of action potential by using linear curve fitting of one well known electrophysiological model.
Keywords:
Cellular Automata, Action Potential Propagation,cardiac tissue, Isotropic Pattern, accurate shape of cardiac actionpotential.
1
13719
A new Cellular Automata Model of Cardiac Action Potential Propagation based on Summation of Excited Neighbors
Abstract:
The heart tissue is an excitable media. A Cellular Automata is a type of model that can be used to model cardiac action potential propagation. One of the advantages of this approach against the methods based on differential equations is its high speed in large scale simulations. Recent cellular automata models are not able to avoid flat edges in the result patterns or have large neighborhoods. In this paper, we present a new model to eliminate flat edges by minimum number of neighbors.
Keywords:
Cellular Automata, Action Potential Simulation,Isotropic Pattern.