|Commenced in January 1999 || Frequency: Monthly || Edition: International|| Paper Count: 3 |
Medical, Health, Biomedical, Bioengineering and Pharmaceutical Engineering
Therapeutic Product Preparation Bioprocess Modeling
An immunomodulator bioproduct is prepared in a
batch bioprocess with a modified bacterium Pseudomonas
aeruginosa. The bioprocess is performed in 100 L Bioengineering
bioreactor with 42 L cultivation medium made of peptone, meat
extract and sodium chloride. The optimal bioprocess parameters were
determined: temperature – 37 0C, agitation speed - 300 rpm, aeration
rate – 40 L/min, pressure – 0.5 bar, Dow Corning Antifoam M-max.
4 % of the medium volume, duration - 6 hours. This kind of
bioprocesses are appreciated as difficult to control because their
dynamic behavior is highly nonlinear and time varying. The aim of
the paper is to present (by comparison) different models based on
The analysis criteria were modeling error and convergence rate.
The estimated values and the modeling analysis were done by using
the Table Curve 2D.
The preliminary conclusions indicate Andrews-s model with a
maximum specific growth rate of the bacterium in the range of
Assessment of Microbial Pollution of the Dental Chairs Water System (Pseudomonas aeruginosa) in the City of Tripoli, Libya
This study mainly aims at assessing the level of
microbial pollution of the water used in the chair system in dental
clinics. For this purpose 36 samples have been randomly collected
from a number of dental surgeries in the city of Tripoli in Libya.
However, 32 of the samples have tested positive to microbial
pollution including 13 of the samples, which have tested positives to
Pseudomonas aeruginosa. Based on the results of the test a further
investigation of the biofilms incorporated within the dental chair
system has been conducted. The laboratory tests of biofilms with
similar design to those found in dental chairs have proved that
bacterial pollution takes place through saliva of the patients who use
the chairs, and that this saliva is rich with nutrients which provides a
suitable breeding ground for all types of bacteria.
Determination of Electromagnetic Properties of Human Tissues
In this paper a computer system for electromagnetic
properties measurements is designed. The system employs Agilent
4294A precision impedance analyzer to measure the amplitude and
the phase of a signal applied over a tested biological tissue sample.
Measured by the developed computer system data could be used for
tissue characterization in wide frequency range from 40Hz to
110MHz. The computer system can interface with output devices
acquiring flexible testing process.