Scholarly Research Excellence

E Aboutaleb

Publications

1

Publications

1
15432
Vincristine-Dextran Complex Loaded Solid Lipid Nanoparticles for Drug Delivery to the Brain
Abstract:
The purpose of this work was to inspect the potential of vincristine-dextran complex loaded solid lipid nanoparticles for drug delivery to the brain. The nanoparticles were stained with a fluorescence dye and their plasma pharmacokinetic and brain concentrations were investigated following injection to rats. The result revealed a significant improvement in the plasma concentration profile of the SLN injected animals as well as a sharp increased concentration in the brains.
Keywords:
Brain, Coumarin-6, Nanoparticles, SLN.